MCP thiab Kev Tiv Thaiv Cancer - Cov tswv yim proactive
Kev tiv thaiv thoob plaws teb chaws txhua xyoo Kev Tiv Thaiv Kev Nkag Mus Txog Lub lim tiam lub limtiam uas tsis tseem ceeb:mob kha xawTseem nyob rau hauv lub ntiaj teb kev hem thawj uas yuav tsum ua kom paradigm kev hloov pauv . Thaum}}}}} Kev Tshawb Fawb Txog Kev Cia Siab,Tsawg kawg yog ib feem peb ntawm malignies yog tiv thaiv tau(Leej twg) . Qhov no xav tau qhov kev hloov pauv tseem ceeb los ntawm kev kho-centric rauKev Tiv Thaiv-canny Cancer Control{. Central rau qhov kev hloov no yog kev kawm tawm suab-backedHloov Citrus Pectin (MCP), nws lub luag haujlwm hauvmob kha xawKev cuam tshuam yog tau txais kev siv tau zoo .
Tus nqi ntawm kev tsis saib xyuas: Vim li cas kev tiv thaiv tawm ntawm kev kho mob cancer
Kev kuaj mob ncua kev txom nyem ploj zuj zus kev muaj sia nyob rau .}}} Kev tshuaj ntsuam xyuas kom ntxovmob kha xawKev Tshawb Xyuas-Zoo Ua Rau Thaum Ntxov Kho Qhov Kawg Tiv Thaiv Kev Tiv Thaiv {}} Tus cwjpwm ua si nrog kev tshawb fawb tshwm simMCP thiab Cancerkev pheej hmoo me me .
Nkag siab tus yeeb ncuab: Qhov xwm thiab kev txhim kho cov kabmob kheesxaws
Kev hloov kho mob kheesxaws los ntawm kev hloov pauv ntawm cov hlwb " Nws yog lub caij nyoog ntev heev, kev sib hloov pauv ntawm qhov kev hloov pauv ntawm kev ua kom muaj zog rau kev ua kom zoo nkauj, "Tiv thaiv lawv kom tau cov neeg ntxeev siab ua haujlwm"Tswj kev tiv thaiv thiab txhim kho kev tiv thaiv yog lub hauv paus sab hauv sab hauv.
Lub tsev defenses: ib multi-fawm-fawm cancer tiv thaiv lub tswv yim
Kev ua tiav qhov hloov mus rau "Kev Tiv Thaiv-Chaw" txoj kev yuav tsum muaj ntau lub tswv yim zoo:
Tsis txhob muaj sab nraud carcinogenic yam:
Ib puag ncig kev pheej hmoo:Zam kev paub txog Carcinogens xws li qee cov khoom siv tshuaj lom neeg siv tshuaj, dyes, asbestos, thiab puring}}}}}
Nyob Chaw Nyob:Xyuas kom meej cov tsev tshiab kho kom huv si (tshwj xeeb tshaj yog cov cua sov kom txo cov pa phem hauv tsev sab hauv {}}
Kev nyab xeeb hauv chav ua noj:Txhawb kev ua noj ua haus xws li steaming thiab boiling kom txo qis kev sib raug zoo los ntawm high-kub frying .
Kev puag kev noj qab nyob zoo (qhov "dread" ntawm cov qog nqaij hlav cancer):
Ua kom haum:Nce zis tso zis ua rau lub concentration ntawm cov kev muaj peev xwm carcinogens hauv zis, txo lawv cov voos hauv lub kaw lus tso zis [1].
Kev tawm dag zog tsis tu ncua:Kev ua kom lub cev muaj zog sib xws yog "cov tshuaj zoo" rau kev ua kom muaj zog thiab ua kom lub cev muaj kev tiv thaiv kev tiv thaiv kev noj qab haus huv
Tswj kev cia siab:Mob siab ntev, ntxhov siab, kev ntxhov siab, kev npau taws thiab pw tsaug zog zoo nkauj yog qhov tseem ceeb .
Kev noj haus muaj zog (Xyaum "kev tiv thaiv kab mob los ntawm kev noj haus ." noj mov, zom kom huv; Qhia meej tias kev noj zaub mov noj txiv hmab txiv ntoo, zaub, thiab cov nplej muaj ntau; nruj me ntsis txwv cov ntsev ntau, cov khoom noj muaj roj ntau; thiab txiav luam yeeb thaum haus dej haus cawv [4] {{4 4}}
MCP thiab Kev Tiv Thaiv Cancer: Mechanisms siv tau los ntawm kev tshawb fawb
Lub tsev ua zaub mov muaj txiaj ntsig, kev tshawb fawb txog cov kev noj zaub mov noj kom zoo rau cov tswv yim tiv thaiv kev tiv thaiv kev tiv thaiv nquag.Hloov Citrus Pectin (MCP), vim nws cov khoom siv bioacties tseem ceeb, tau ua kom zoo nkauj thiab pib tshawb nrhiav lub xov tooj ntawm cov neeg mob kheesxaws {}}
Yog leejtwg thiab cov khoom:MCP yog muab tau los ntawm tev ntawm cov txiv hmab txiv ntoo thiab ua tiav los ntawm kev noj haus dej kom zoo nkauj thiab cov roj ntsha tsis zoo, ua kom muaj kev nqus tau zoo thiab muaj peev xwm ntau dua hauv tib neeg lub cev [5] {.
Calis Cancer Kev Tiv Thaiv Kev Siv Hluav Taws Xob & Kev Tshawb Fawb:
Muaj pes tsawg zog hnyav hlau chelation, txo cov carcinogenic triggers:Cov qauv ntawm MCP muaj cov pab pawg muaj teeb meem caracturonic, txhuas,}} Nqus cov complex uas txhawb nqa lawv cov quav, txo qis rau lub cev hnyav lub cev [6, 7]} Cov hlau hnyav yog tsim carcinogens; Lub sij hawm ntev tau tuaj yeem ua rau DNA kev puas tsuaj thiab cellular carcinogenesis {} MCP ncaj qha rau cov hlau hnyav los ntawm cov tshuab hnyav.
Kev txwv ntawm Cancer Cancer Adhesion thiab Metastasis (Anti-clumping "nyhuv):Kab mob kheesxaws cov kabmob overexpression ib cov protein ntawm lawv qhov hu uaGalectin -3. galectin -3 Cov kua nplaum ntawm cov qog nqaij hlav cancer8 Cov kab mob cancer endiliting (sib sau Micrometastases) thiab anchoring rau cov chaw tshiab scitas [8] {5 5}}Cov txheej txheem tseem ceeb ntawm MCP lus dag nyob rau hauv nws cov qauv molecular, muaj cov seem galacular, khi cov hlua khi tshwj xeeb rau galecin -3.MCP ua raws li lub siab-authinity ligand rau galectin {}}}}} {}}} Cov qog nqaij hlav Metabasis, yog li:
Thaiv cov galectin -3- Kev kho hluav taws xob sib xyaw, tiv thaiv cov qog nqaij hlav cancer los ntawm "clumping" rau hauv cov agon.
Inhibiting cancer cancer cancer rau vascular endothelium, tabkoov cov ntshav siab) thiab ntxiv cov organs nyob rau hauv) [10] .
Cuam tshuam cov pro-tumorigenic thiab pro-angiogenic lub luag haujlwm ntawm Galticin-3}} tsis pub dhau lub qog mis nyuj microenviror [11] {4 4}}
Ntau hauv cov kev sim vito thiab cov tsiaj qauv kev kawm paub tseeb tias MCP ntxiv rau metastasis hauv ntau cov qog nqaij hlav (postate, mis, melanoma) [{{4 4}
Kev tiv thaiv kab mob thiab txhim kho cov tshuaj tiv thaiv kab mob:Dhau ntawm nws cov teebmeem kev cuam tshuam ncaj qha, MCP, ua ib nrab noj zaub mov freat {{{. mcp thiab nws cov metabolites yuav Indirectly txhawb lub cev kev soj ntsuam ntawm lub cev thiab kev tshem tawm cov pa ntawm cov kab mob txawv txav thiab txhim kho}} g}}
Tsuas yog los ntawm kev hais kwv txhiaj ua ke kom txav mus rau qhov kev tiv thaiv kab mob cancer, ua tiav kev hloov pauv ntawm cov tshuaj tiv thaiv kev nquag ua rau tswj tsis muaj zog {}}
Txheeb xyuas cov qog nqaij hlav & mcp mechanisms
{{01. hydration & carcinogen dilution:
Michaud, d . s} s} .}} Lub pob Askiv tshiab hauv England ntawm cov tshuaj, 340 (18),1390-1397.
[Txhawb cov zis kom txo cov carcinogen raug]
{{0 {}} Kev Ua Ke & Tiv Thaiv:
Pedersen, l ., thiab al. {} {} {(7), {{}
[Cov kev sib txuas lus ntawm kev tawm dag zog thiab cov tshuaj tiv thaiv mob cancer immunity]
{{0 {0} Kev ntxhov siab & tiv thaiv tsis tau Dysregulation:
Moreno-smith, m .}}}}}}}}}}}}}}, 1863-1881.
[Cov kev siv dag ntxias tsis muaj kev tiv thaiv kab mob tiv thaiv kab mob]
4. Kev noj haus & Cancer REASE:
Kev Tshawb Fawb Kev Tshawb Fawb Txog Ntiaj Teb Nyiaj Txiag Nyiaj Txiag
[Tso Cai Daim Ntawv Tshaj Qhia Txog Kev Noj Qab Haus Huv-Cancer Cable]
5. mcp bioavailability:
Khotimchenko, m . y . {{{4} {} {} {} {} {116300.
[Cov qauv coj thiab ua haujlwm ntawm MCP]
6. mcp chelates txhuas / cadmium (tib neeg mus sib hais):
Eliaz, Kuv {., thiab al . {}} pytotheraply kev tshawb fawb, 20 (10),859-864.
[Pov thaiv cov ntaub ntawv pov thawj ntawm MCP's Detox nyhuv]
{{07. mcp Binds Arsenic (Tsiaj Kev Kawm):
Zhao, z {. y .} {} {} {{}, {{, {{9}289-299.
[MCP txo cov hlau-cov tsis muaj kuab lom]
8.} Galticin -3 hauv cov qog metastasis:
Liu, f. t}}}}}}} qhov kev soj ntsuam xyuas Cancer, 5 (1), {9}29-41.
* [Seminal tshuaj xyuas ntawm gal -3 'sole hauv mob cancer] *
9. mcp binds & inhibits granecin -3:
Nangia-Makker, P .} {2} {} {} {} {(64 (24), {8} {8}
* [Daim Ntawv Landmark: MCP Blocks Gal -3} rau suppress Metastasis] *
10.} Galticin -3 Kev Kho Mob Tum Adhesion / Angiogenesis:
Glinsky, v . v}}} {}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}} {} {}
* [Cov ntsiab lus Molecular txoj kev cuam tshuam nrog gal -3}}}}} inhibition] *
{{011. mcp inhibits prostate prostateance:
Pienta, k {. j {}} {{4 4}}}}}}} 348 - 353.
[Cov pov thawj thaum ntxov ntawm MCP's Anti-Metastatic Kev Ua]
{{012. mcp block ntawm melanoma Lung Colonization:
Platt, v . d {} {{{{} {{} {} {} {} {} {} {}}}}} {}}}}} {}}}}} {} {}
* [MCP cuam tshuam Metastasis ntawm gal -3 tsom] *
13. mcp suppressesisceancy cancer MetaSasis:
Johnson, k . d}}} {} {} {} {} {, 11140 - 11145.
[MCP induces cancer cancer kev tuag hauv lub plab]
{{014. scfas (Butyrate) & anti-cancer angunity:
Singh, n {., thiab al {{{{{5} {{5} {, 18 - 139.
[LINKS OUT Fermentation cov khoom rau kev tiv thaiv kab mob]
15. mcp Enhances NK Cell Haujlwm:
Ramachandran, c ., thiab al {{1} {} {} Cov Lus Teb Cancer los ntawm kev kho mob qog Cancer, 16 (4), NP1-NP10.
[Cov ntaub ntawv pov thawj ncaj qha ntawm MCP lub cev tiv thaiv kab mob-Boosting nyhuv]